Release Pattern of Liposomal Bupivacaine in Artificial Cerebrospinal Fluid

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Release Pattern of Liposomal Bupivacaine in Artificial Cerebrospinal Fluid.

OBJECTIVE We aimed to compare the possible controlled release profile of multilamellar liposomal bupivacaine formulations with non-liposomal forms in artificial cerebrospinal fluid (CSF) under in vitro conditions. METHODS Liposome formulations were prepared using a dry-film hydration method. Then, an artificial CSF-buffered solution was prepared. Bupivacaine base with liposomal bupivacaine ba...

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ژورنال

عنوان ژورنال: Turkish Journal of Anesthesia and Reanimation

سال: 2016

ISSN: 2149-0937,2149-276X

DOI: 10.5152/tjar.2016.02438